Synthetic Route of 5424-01-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5424-01-1, name is 3-Aminopyrazine-2-carboxylic acid, This compound has unique chemical properties. The synthetic route is as follows.
Compound 1 (5 g, leq) was added to methanol (50 ml)Ice water bath by adding concentrated sulfuric acid (4eq),The reaction was stirred at room temperature,TLC showed complete reaction,concentrate,Saturated sodium carbonate adjusted to pH = 8,Filter, 50 dry 2h,A brown solid 2 (4.18 g,76%).
The chemical industry reduces the impact on the environment during synthesis 3-Aminopyrazine-2-carboxylic acid. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Central South University; Liu Fengliang; Li Cuiqin; (19 pag.)CN106866553; (2017); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem