Application of 345311-03-7, The chemical industry reduces the impact on the environment during synthesis 345311-03-7, name is tert-Butyl 5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate, I believe this compound will play a more active role in future production and life.
1 ,1-Dimethylethyl 5,6-dihydroimidazo[1 ,2-a]pyrazine-7(8/-/)-carboxylate (118) (1.563 g, 7 mmol) and NCS (0.935 g, 7.00 mmol) were heated at 80 0C for 2 h in toluene (30 ml_). The solvents were removed in vacuo and the residue was purified by flash chromatography (Isolera, 50 g, 0-100% ethyl acetate/iso-hexane) to afford product in 1.55 g. LC/MS = 258/260 (M+H)+, retention time = 0.64 minutes (2 minute method).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, tert-Butyl 5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; GLAXO GROUP LIMITED; DEAN, David Kenneth; MUNOZ-MURIEDAS, Jorge; SIME, Mairi; STEADMAN, Jon Graham Anthony; THEWLIS, Rachel Elizabeth Anne; TRANI, Giancarlo; WALL, Ian David; WALTER, Daryl Simon; WO2010/125101; (2010); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem