Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 109-08-0, name is 2-Methylpyrazine, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 109-08-0
General procedure: 2-aminophenyl ketones 1 (0.3 mmol), methylazaarenes 2 (0.6 mmol), NH4OAc (0.6 mmol), CuCl2 (20 mol %), TFA (50 mol %), DMF (2.0 mL) were added to a 25mL Schlenk tube under O2 atmosphere with magnetic stirrer bar. The reaction mixture was stirred at 120 _C (oil bath temperature) for 24 h. After the reaction was finished (monitored by TLC), the mixture was cooled to room temperature, quenched with solution of NaHCO3 (10 mL) and extracted with EtOAc (3 _ 10 mL). The combined organic layers were dried over anhydrous MgSO4 and the solvent was removed under vacuum. The crude product was purified by column chromatography (EtOAc/hexanes) on silica gel.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 109-08-0.
Reference:
Article; Liang, En; Wu, Yinrong; Chen, Jiewen; Xiong, Wei; Zhao, Jinwu; Yao, Xingang; Tang, Xiaodong; Tetrahedron; vol. 75; 52; (2019);,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem