Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4858-85-9, name is 2,3-Dichloropyrazine, This compound has unique chemical properties. The synthetic route is as follows., Formula: C4H2Cl2N2
2,3-Dichloropyrazine (III-9) (500 mg, 3.36 mmol) and 4-chlorophenol (II-17) (431 mg, 3.36 mmol) were dissolvedin DMF (10 mL), potassium carbonate (557 mg, 4.03 mmol) was added and the mixture was stirred at 90C for 15 hr.The reaction mixture was cooled, water was added, and the mixture was extracted with ethyl acetate. The organic layerwas washed successively with water and saturated brine, and the solvent was evaporated under reduced pressure. Theresidue was purified by silica gel column chromatography (n-hexane:ethyl acetate = 100:0 ? 85:15) to give compound(IV-102) (yield 809 mg, quantitative) as a white solid
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 4858-85-9.
Reference:
Patent; Kaken Pharmaceutical Co., Ltd.; WATANABE, Atsushi; SATO, Yuuki; OGURA, Keiji; TATSUMI, Yoshiyuki; (331 pag.)EP3351533; (2018); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem