In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 17890-77-6, name is 3-Amino-6-bromopyrazine-2-carboxamide belongs to Pyrazines compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 17890-77-6
10 g of 3-amino-6-bromopyrazine-2-carboxamide was added to 120 ml of tetrahydrofuran, 0.1 g of tetrakis(triphenylphosphine)palladium and 12.6 g of sodium carbonate were added, and then 14 g of 3-chloro-5-methyl was added. The phenylboronic acid was heated to reflux for 5 hours and concentrated. Water and ethyl acetate were added to extract and the mixture was separated. The organic phase was collected and concentrated. The residue was separated on a silica gel column to give 7 g of 3-amino-6-(3-chloro-5-methylphenyl)pyrazine-2-carboxamide
The synthetic route of 17890-77-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Changsha Shencheng Biological Technology Co., Ltd.; Bu Gonggaofamingren; (5 pag.)CN107513041; (2017); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem