Synthetic Route of 3149-28-8, The chemical industry reduces the impact on the environment during synthesis 3149-28-8, name is 2-Methoxypyrazine, I believe this compound will play a more active role in future production and life.
General procedure: Perfluorobutanesulfonyl azides 1a (715 mg, 2.2 mmol) and pyrazine 2a (2.0 mmol) was mixed without solvent at room temperature, this reaction mixture stirred for 8 h at 120 C, TLC analysis showed the reaction was completed. The product 3aa was obtained by flash column chromatography (using petroleum ether/ethyl acetate=2:1 as eluant) as a yellow solid in 34% yield (234 mg).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Methoxypyrazine, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Xiong, Wanting; Zhang, Hongfei; Xin, Yong; Zhu, Shizheng; Tetrahedron; vol. 67; 12; (2011); p. 2232 – 2237;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem