Synthetic Route of 1053656-22-6, The chemical industry reduces the impact on the environment during synthesis 1053656-22-6, name is 7-tert-Butyl 2-ethyl 5,6-dihydroimidazo[1,2-a]pyrazine-2,7(8H)-dicarboxylate, I believe this compound will play a more active role in future production and life.
Stage 2: A solution of 7-tert-butyl 2-ethyl 5,6-dihydroimidazo[1,2-a]pyrazine-2,7(8H)-dicarboxylate (300 mg, 1.02 mmol) in THF (15 ml) was cooled to -78 C., and DIBAL-H (1 M in hexane, 2.0 ml, 2.0 mmol) was added slowly under an N2 atmosphere. The reaction mixture was stirred for 1 hour at that temperature and then Na2SO4¡Á10H2O was added until no further evolution of gas was observed. Further sodium sulfate was added, the solution was filtered, and the residue was washed with DCM (25 ml). The filtrate was concentrated and the resulting crude product (450 mg) was used in the next stage without further purification.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 7-tert-Butyl 2-ethyl 5,6-dihydroimidazo[1,2-a]pyrazine-2,7(8H)-dicarboxylate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; GRUENENTHAL GmbH; US2010/173889; (2010); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem