Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 61655-77-4, name is 2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine, This compound has unique chemical properties. The synthetic route is as follows., Application In Synthesis of 2-Chloro-6-(4-methylpiperazin-1-yl)pyrazine
General procedure: A microwave tube filled with compound 2 (0.35 mmol), alkoxy heteroaromatic chloride or amine heteroaromatic chloride (0.38 mmol), bis(triphenylphosphine)palladium(II) dichloride (0.010 mmol), 2 M potassium carbonate (1.7 mmol) in dioxane : ethanol (2 : 3) was heated in the microwave reactor at power 100 W and 120 C for 10 min. After solvent was removed in vacuo, the residue was treated with ethyl acetate and washed with water. The obtained organic layer was dried over anhydrous sodium sulfate, and concentrated in vacuo. The residue was purified by flash column chromatography over silica gel.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 61655-77-4.
Reference:
Article; Lee, Jinho; Park, Jongseong; Hong, Victor Sukbong; Chemical and Pharmaceutical Bulletin; vol. 62; 9; (2014); p. 906 – 914;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem