Discovery of 32587-10-3

According to the analysis of related databases, 32587-10-3, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 32587-10-3, name is 3-Aminopyrazine-2-carboxamide, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 32587-10-3

Step 2: Synthesis of Intermediate C’ as described in the general scheme: 2-amino-3-amido-5-bromopyrazine A mixture of B’ (210 g, 1.52 mM), acetic acid (630 mL) and sodium acetate tri-hydrate (310 gm, 2.28 mM) is warmed up to 50 C. To this solution is added bromine (93.43 mL, 1824 mM) in acetic acid (105 mL) in 1.5 hrs and the mixture is stirred for 30 min at 50-55 C. The reaction mixture is cooled to 15 C., water (2.1 L) is added over 20-30 min and the resulting suspension is stirred for another 30 min. The Solid is isolated by filtration, washed with water (210 mL*2) and dried at 45 C. under vacuum to afford C’, used in the next step without further treatment.

According to the analysis of related databases, 32587-10-3, the application of this compound in the production field has become more and more popular.

Reference:
Patent; WIGERINCK, Piet Tom Bert Paul; ANDREWS, Martin James Inglis; De WEER, Marc Maurice Germain; SABOURAULT, Nicholas Luc; KLUGE, Stefan Christian; US2011/118269; (2011); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem