Related Products of 75907-74-3,Some common heterocyclic compound, 75907-74-3, name is (3,5,6-Trimethylpyrazin-2-yl)methanol, molecular formula is C8H12N2O, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
(4) In a round bottom flask, add (4) (1.0 equiv), add DCM as solvent, add phosphorus tribromide (1.0-2.0 equiv) at 0 C, stir the reaction at 25 C for 1 h, TLC monitoring The formula (4) disappears, and after completion of the reaction, water is added, and dichloromethane is extracted, and the organic layer is collected, dried and concentrated to give a compound of the formula (5) as a white solid.
The synthetic route of 75907-74-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Chengdu University; Zou Liang; Zhang Jinming; Liu Xiaowei; Li Wei; Li Hanmei; Zhang Yan; Zhang Lele; Yang Yong; (14 pag.)CN110101872; (2019); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem