In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 313339-92-3, name is 3,5-Dichloropyrazine-2-carbonitrile belongs to Pyrazines compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C5HCl2N3
11625] (R)-3-Amino-N,N-dimethylazepane- 1 -carboxamide (508) (.-200 mg crude) was dissolved in THF (7 mE), and DIEA (0.30 mE, 1.7 mmol) was added, followed by 3,5- dichloropyrazine-2-carbonitrile (100 mg, 0.57 mmol). The reaction was stirred at RT for 12 hours. The solvents were removed under reduced pressure, and the residue was purified by silica column chromatography (MeOR, DCM) to give (R)-3-(6-chioro-5-cyanopyrazin-2-ylamino)-N,N-dimethy- lazepane-1-carboxamide (509) (53 mg, 0.16 mmol, 14% yield over 3 steps).
The synthetic route of 313339-92-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; JIA, Zhaozhong J.; CHEN, Wei; THOMAS, William D.; US2015/158865; (2015); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem