Related Products of 4744-50-7, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 4744-50-7 as follows.
17a. 3-(N-(2-Methyl-2-sulfanylpropyl)carbamoyl)pyrazine-2-carboxylic acid A suspension of 2-mercapto-2-methyl-1-propylamine hydrochloride (1.14 g, 8 mmol) in dichloromethane (15 mL) was cooled to 0 C. and then treated with triethylamine (1.23 mL, 0.9 g, 8.9 mmol) followed by furano(3,4-b)pyrazine-5,7-dione (1.2 g, 8 mmol). The reaction mixture was stirred at 0 C. for 40 minutes then at room temperature for 1 hour. The solvent was removed by evaporation and the residue triturated with hexane/ether to give the title compound (1.2 g, 59%). Mp 141-144 C. 1H NMR (300 MHz, DMSO-d6) delta8.83-8.86 (m, 3H), 3.45 (d, J=6.4 Hz, 2H), 2.87 (s, 1H), 1.33 (s, 6H).
According to the analysis of related databases, 4744-50-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Fang, Xinqin; Garvey, David S.; Gaston, Ricky D.; Lin, Chia-En; Ranatunga, Ramani R.; Richardson, Stewart K.; Wang, Tiansheng; Wang, Weiheng; Wey, Shiow-Jyi; US2003/203915; (2003); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem