Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 313339-92-3, name is 3,5-Dichloropyrazine-2-carbonitrile, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C5HCl2N3
Under inert atmosphere, a mxture of 3,5dichoropyrazine2carbonitrNe (1 equiv.), 2 methylpyridine3boronic acid pinacol ester (I equiv.), cesium carbonate (3 equiv.) and PdCl2(dppf).CH2C2 (0.1 equiv.) in doxane (0.10 moLL1) and water (0.80 moLL1) was heatedat 80 C for 1 hour. The reaction mixture was hydroysed and extracted twice with ethy acetate. The organic layers were combined, washed with brine, dried over MgSO4, concentrated under vacuum and purfied by flash column chromatography on sWca gel (usng 20% to 100% ethy acetate (EtOAc) in cyclohexane as eluent) to afford the product as a brown solid in 57% yield. 1HNMR (400 MHz, DMSOD6): 9.17 (s, 1H, Ar); 8.65 (dd, J4.8, 1.7 Hz, 1H,Ar); 8.02 (dd, J 7.8, 11 Hz, 1H, Ar); 7.46 (dd, J 7.8, 4.8 Hz, 1H, Ar); 2.62 (s, 3H, CH3). M/Z (M[35Cl]+H) = 230.9.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 313339-92-3.
Reference:
Patent; MAVALON THERAPEUTICS LIMITED; BLAYO, Anne-Laure; CATELAIN, Thomas; DORANGE, Ismet; GENET, Cedric; MANTEAU, Baptiste; MAYER, Stanislas; SCHANN, Stephan; (290 pag.)WO2018/206820; (2018); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem