Simple exploration of 399-66-6

The chemical industry reduces the impact on the environment during synthesis [1,2,4]Triazolo[1,5-a]pyrazine. I believe this compound will play a more active role in future production and life.

Related Products of 399-66-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 399-66-6, name is [1,2,4]Triazolo[1,5-a]pyrazine, This compound has unique chemical properties. The synthetic route is as follows.

Stage 4. Platinum (IV) oxide (2.75 g, 12.1 mmole) was added to a suspension, saturated with nitrogen, of CaO (9.30 g, 166 mmole) and [ 1, 2 , 4 ] -triazolo [ 1, 5-a] pyrazine (18.1 g, 151 mmole) in methoxyethanol (150 ml) . The reaction mixture was stirred for 21.5 hours under a hydrogen atmosphere. The catalyst was filtered off through filter earth and washed with DCM/ethanol (9:1). The filtrate was concentrated, and the solvent was removed firstly with toluene and then with 2-propanol. The residue was taken up in ethyl acetate, filtered again through filter earth, washed with ethyl acetate, and concentrated. The residue was washed with hot 2-propanol and concentrated in vacuo.

The chemical industry reduces the impact on the environment during synthesis [1,2,4]Triazolo[1,5-a]pyrazine. I believe this compound will play a more active role in future production and life.

Reference:
Patent; GRUeNENTHAL GMBH; WO2009/90055; (2009); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem