Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 873-40-5, name is 2,3,5-Trichloropyrazine, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 873-40-5
28.5 g (152.65 mmol) of 2,3,5-trichloropyrazine, 23.8 g (152.65 mmol) of 2-chlorophenylboronic acid, 63.3 g (457.9 mmol) of K2CO3 and 800 ml / 200 ml of THF/H2O were added under nitrogen atmosphere and stirred. 5.3 g (4.58 mmol) of Pd (PPh3) 4 was added at 40 DEG C, and the mixture was stirred at 80 DEG C for 12 hours. After completion of the reaction, the reaction mixture was extracted with dichloromethane. The organic layer was dried over MgSO4 and filtered under reduced pressure. The filtered organic layer was distilled under reduced pressure, and 12 g (yield: 30%) of 2,5-dichloro-3- (2-chlorophenyl) pyrazine was obtained by column chromatography.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 873-40-5.
Reference:
Patent; Doosan Co., Ltd; Kim Tae-hyeong; Bae Hyeong-chan; Son Hyo-seok; Baek Yeong-mi; Park Ho-cheol; (53 pag.)KR101920101; (2018); B1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem