Application of 75907-74-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 75907-74-3, name is (3,5,6-Trimethylpyrazin-2-yl)methanol belongs to Pyrazines compound, it is a common compound, a new synthetic route is introduced below.
In the reaction flask, 2-hydroxymethyl-3,5,6-trimethylpyrazine (3 g, 0.02 mol) was added, Dissolved in 20 mL of dichloromethane, The ice bath was added dropwise with stirring Thionyl chloride (3 mL, 0.04 mol), Stirring reaction 1.5h TLC monitoring to the reaction is complete, The solvent and the remaining dichlorosulfoxide were evaporated under reduced pressure to give a pale yellow mass 2-chloromethyl-3,5,6-trimethylpyrazine 3.2 g, 20 mL of DMF (N, N-dimethylformamide) was added.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, (3,5,6-Trimethylpyrazin-2-yl)methanol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; KPC Pharmaceuticals, Inc; song, LI MING; Bai, Fei; Yang, ZHAO XIANG; (15 pag.)CN104341358; (2016); B;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem