Research on new synthetic routes about 912773-24-1

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 912773-24-1.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 912773-24-1, name is 6-Bromoimidazo[1,2-a]pyrazine, This compound has unique chemical properties. The synthetic route is as follows., Formula: C6H4BrN3

Example 17-8 Synthesis of 6-bromo-3-iodo-imidazo[1,2-a]pyrazine 6-Bromoimidazo[1,2-a]pyrazine 16* (1.98 g, 0.01 M) was added to N-iodosuccinimide (2.46 g, 0.011 M) in acetonitrile (50 ml). The resulting mixture was heated at reflux overnight. The solvent was evaporated in vacuo and the residue was treated with sodium carbonate solution and extracted with ethyl acetate (3 x 200 ml). The combined extracts were dried over magnesium sulphate and evaporated in vacuo to give a pale brown solid. The solid was washed with ethyl acetate (10 ml) to give 2.23 g of the desired product. 1H-NMR (400 MHz, CDCl3): delta = 7.88 (1 H, s, ArH), 8.25 (1 H, s, ArH), 8.81 (1 H, s, ArH).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 912773-24-1.

Reference:
Patent; Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.; Ullrich, Axel; Falcenberg, Mathias; EP2818471; (2014); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem