Brief introduction of Pyrazine-2-carboxylic acid

According to the analysis of related databases, 98-97-5, the application of this compound in the production field has become more and more popular.

98-97-5, Adding a certain compound to certain chemical reactions, such as: 98-97-5, name is Pyrazine-2-carboxylic acid, belongs to Pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 98-97-5.

(a) 2-pyrazine carboxylic acid, 104.3 gm, and 105.9 gm thionyl chloride were added to 800 ml methylene chloride and 5 ml dimethylformamide. The system was heated to reflux, at which point gas evolution took place. The system was stirred at reflux until gas evolution ceased, after about 5 hours, to give the 2-pyrazine carboxylic acid chloride. The solution was cooled to room temperature and transferred to a dropping funnel for use in Step (b) without further isolation.

According to the analysis of related databases, 98-97-5, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Chevron Research Company; US4504484; (1985); A;; ; Patent; Chevron Research Company; US4588735; (1986); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem