Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 55557-52-3, name is 3-Chloropyrazine-2-carbonitrile, This compound has unique chemical properties. The synthetic route is as follows., 55557-52-3
To a solution of 3-chloropyrazine-2-carbonitrile (15.0 g, 108 mmol) in AcOH (200 mL) was added Raney Ni (3 g, in water), and the mixture was stirred for 48 h under an atmosphere of hydrogen with a balloon at rt. The mixture was filtered and the filtrate was concentrated in vacuo to give a crude product, which was dissolved in 250 mL of aqueous HC1 (2M) and extracted with EtOAc (200 mL x 2). The aqueous layer was concentrated under vacuo to give 14.5 g of (3-chloropyrazin-2-yl)methanamine hydrochloride as a brown solid which was used in the next step without further purification.
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Reference:
Patent; PRINCIPIA BIOPHARMA INC.; GOLDSTEIN, David; OWENS, Timothy D.; (121 pag.)WO2016/210165; (2016); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem