Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 15707-23-0, name is 2-Ethyl-3-methylpyrazine, This compound has unique chemical properties. The synthetic route is as follows., 15707-23-0
[0239] A mixture of 2-methyl-3-ethylpyrazine (1.0 g, 8.19mmol), selenium dioxide (1.8 g, 16.38 mmol), and diatomaceous earth (1.8 g) in dioxane (20ml) was refluxed for overnight. The mixture was allowed to cool to room temperature. The solid material was removed by filtration through diatomaceous earth. The solvent was evaporated under reduced pressure. The crude product was washed with water (3 x 10 ml), extracted with ethyl acetate (3 x 20 ml), dried with Na2S04 and concentrated. The crude product was used directly for the next step reaction without purification. LC/MS = 137 [M+l].
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.
Reference:
Patent; MERCK SHARP & DOHME CORP.; KUANG, Rongze; TING, Pauline; ALI, Amjad; WU, Heping; BERLIN, Michael; STAMFORD, Andrew; WANG, Hongwu; ZHOU, Gang; KIM, David; DENG, Qiaolin; LIM, Yeon-Hee; YU, Younong; (201 pag.)WO2016/81290; (2016); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem