The chemical industry reduces the impact on the environment during synthesis 1458-18-0, name is Methyl 3-amino-5,6-dichloropyrazine-2-carboxylate, I believe this compound will play a more active role in future production and life. 1458-18-0
To a suspension of methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate (IVa) (5.55 g, 25.0 mmol) in 2-propanol (50 mL) was added hexamethyleneimine (2.73 g, 3.1 0 mL, 27.5 mmol) and the mixture was stirred at room temperature. Diisopropyethylamine (3.55 g, 4.79 mL, 27.5 mmol) was then added and the reaction mixture was heated at reflux. After 2 h the reaction was allowed to cool to room temperature, which caused the product to crystallize. The solid product was collected by vacuum filtration and washed with cold 2-propanol followed by diethyl ether. After drying, the desired product (Ilia) was obtained as pink crystals (5.91 g, 83%).
The chemical industry reduces the impact on the environment during synthesis 1458-18-0. I believe this compound will play a more active role in future production and life.
Reference:
Patent; UNIVERSITY OF WOLLONGONG; KELSO, Michael; RANSON, Marie; BUCKLEY, Benjamin; ABOELELA, Ashraf; (103 pag.)WO2018/81863; (2018); A1;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem