33332-29-5, A common compound: 33332-29-5, name is 2-Amino-5-chloropyrazine, belongs to Pyrazines compound, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below.
EXAMPLE 1 3-(5-Chloro-2-pyrazinyl)-1-(2,6-dichlorobenzoyl)urea To a mixture of 250 mg. of 2-amino-5-chloropyrazine in 50 ml. of cold ethyl acetate was added 450 mg. of 2,6-dichlorobenzoylisocyanate and the mixture stirred overnight. The reaction product mixture was concentrated in vacuo to remove the ethyl acetate, and a mixture of ether and hexane added. The solid which precipitated was filtered off. The solid was recrystallized from ethanol to yield product having a melting point of about 201-204 C. The product was identified by elemental analyses and NMR and infrared spectra as 3-(5-chloro-2-pyrazinyl)-1-(2,6-dichlorobenzoyl)urea.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Amino-5-chloropyrazine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Eli Lilly and Company; US4160834; (1979); A;; ; Patent; Eli Lilly and Company; US4083977; (1978); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem