486460-21-3, Adding a certain compound to certain chemical reactions, such as: 486460-21-3, name is 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine, belongs to Pyrazines compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 486460-21-3.
In a 50 ml round bottom flask,0.17 g (0.90 mmol)(Trifluoromethyl) -5,6,7,8-tetrahydro [1,2,4]Triazolo [4,3-alpha] piperazine,2.0 g of a formaldehyde aqueous solution having a mass fraction of 37% and 15 ml of absolute ethanol, stirred at room temperature for 15 minutes,Followed by the addition of 4 – ((R 2 -methylene) amino) -5-R1-2,4-dihydro-3H-1,2,4-triazole-After stirring at room temperature for 1 h,Filter,Washed with absolute ethanol,To obtain the desired solid product.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Nankai University; Wang, Baolei; Li, Zhengming; Zhang, Yan; (13 pag.)CN106749262; (2017); A;,
Pyrazine – Wikipedia,
Pyrazine | C4H4N2 – PubChem